3rd International Caparica Conference in Splicing 2020

13th – 16th  July 2020 | Caparica | Portugal

Oral Speakers

Julie Atkin, PhD

Affiliation: Macquarie University Sydney (Australia)

Title: Avaliable soon.

Lynne-Marie Postovit, PhD

Affiliation: Queen’s University (Canada)

Title: Avaliable soon.

Rachael Natrajan, PhD

Affiliation: The Institute of Cancer Research (United Kingdom)

Title: Avaliable soon.

Tal Shay, PhD

Affiliation: BGU (Israel)

Title: The splicing program of the immune system.

Raul M. Luque, PhD

Affiliation: University of  Cordoba / Maimonides Biomedical Research Institute of Cordoba (Spain)

Title: Avaliable soon.

Francois Bordeleau, PhD

Affiliation: CRChu de Québec (HDQ) – Universite Laval (Canada)

Title: Tumor mechanics and alternative splicing: at the crossroad between regulation and adaptation.

Toru Fujiwara, PhD

Affiliation: University of Tokyo (Japan)

Title: Nutrient-dependent regulation of splicing in Arabidopsis thaliana and their possible roles in low nutrient adaptation.

Naomichi Matsumoto, PhD

Affiliation: Yokohama City University Graduate School of Medicine (Japan)

Title: Avaliable soon.

Yosef Shaul, PhD

Affiliation: Weizmann Institute of Science (Israel)

Title: The spliceosome complex proteins are intrinsically disordered and subjected to a unique mechanism of proteasomal degradation.

Stephen M. Mount, PhD

Affiliation: Univ. of Maryland (United States)

Title: Use of the progerin cryptic splice site in LMNA  is common in wild-type tissues and  is correlated with widespread alterations in isoform ratios.

Corinna Giorgi, PhD

Affiliation: European Brain Research Institute (Italy)

Title: Arc 3’UTR splicing leads to dual and antagonistic effects in fine-tuning Arc expression upon BDNF signaling.

David Tremethick, PhD

Affiliation: The John Curtin School of Medical Research, The Australian National University (Australia)

Title: A new link between chromatin and splicing: histone variants.

Takuro Miyazaki, PhD

Affiliation: Showa University (Japan)

Title: Defective exon junction complex disturbs cholesterol handling in macrophages thereby exacerbating atherosclerosis.

Sandra Cooper, PhD

Affiliation: The University of Sydney; The Children’s Hospital at Westmead; The Children’s Medical Research Institute (Australia)

Title: Pathogenic Abnormal Splicing Due to Intronic Deletions that Induce Biophysical Space Constraint for Spliceosome Assembly.

Patrick Burgon, PhD

Affiliation: Qatar University (Qatar)

Title: Avaliable soon.

Berish Rubin, PhD

Affiliation: Fordham University (United States)

Title: The use of commonly consumed chemical compounds to reverse the impact of the Familial Dysautonomia disease-causing splice-altering mutation: a possible model for other genetic diseases.

Shaodong Dai, PhD

Affiliation: University of Colorado School of Pharmacy (United States)

Title: Avaliable soon.

Sasanka Ramanadham, PhD

Affiliation: University of Alabama at Birmingham (United States)

Title: Avaliable soon.

Oleg Tikhodeyev, PhD

Affiliation: Saint Petersburg State University (Russia)

Title: Autocatalytic RNA splicing as a potential mechanism of epigenetic inheritance.

Olivier Pardo, PhD

Affiliation: Imperial College (United Kingdom)

Title: hnRNPA1 promotes cancer progression in response to FGF2 signalling.

Patricia Coltri, PhD

Affiliation: Instituto de Ciências Biomédicas – Universidade de São Paulo (Brazil)

Title: Avaliable soon.

Penelope Morel, PhD

Affiliation: University of Pittsburgh (United States)

Title: The role of RNA processing factors in regulatory T cell differentiation: does splicing matter?

Kristel Sleegers, PhD

Affiliation: VIB-UAntwerp Center for Molecular Neurology (Belgium)

Title: Splicing of ABCA7 and risk of Alzheimer’s disease.

Alejandro Caceres, PhD

Affiliation: Instituto de Salud Global de Barcelona (ISGlobal) (Spain)

Title: Estimatimation of co-splicing correlations across multiple tissues.

Luciana Haddad, PhD

Affiliation: Universidade de São Paulo (Brazil)

Title: Human DNA variants affecting pre-mRNA splicing: an NGS perspective.

Simon Grelet, PhD

Affiliation: MUSC (United States)

Title: Neurogenesis bridges Tumor Plasticity to Metastasis.

Rendong Yang, PhD

Affiliation: University of Minnesota (United States)

Title: Comprehensive Analysis of Exitron Splicing in Human Cancer.

Gustavo Bressan, PhD

Affiliation: Department of Biochemistry and Molecular Biology – Federal University of Viçosa (Brazil)

Title: Pharmacological intervention of splicing in cancer: targeting the serine/arginine protein kinases (SRPK) to control metastatic melanoma.

Alice Sijts, PhD

Affiliation: Utrecht University (Netherlands)

Title: Cutting and pasting in the immunoproteome of infected cells.

Megan Stevens, PhD

Affiliation: University of Exeter (United Kingdom)

Title: Role of alternative splicing of the apoptosis gene, Bcl-x, in the pathogenesis of diabetic nephropathy.

Ihab Younis, PhD

Affiliation: Carnegie Mellon University Qatar (Qatar)

Title: Targeting Deregulated Splicing in Breast Cancer.

Daria Gaykalova, PhD

Affiliation: Johns Hopkins Medical Institutions (United States)

Title: The role of alternative splicing in head and neck cancer development.

Sureshkumar Balasubramanian, PhD

Affiliation: Monash University (Australia)

Title: Avaliable soon.

Isaac Edery, PhD

Affiliation: Rutgers University (United States)

Title: Splicing of a thermosensitive intron influences midday siesta via trans-regulation of a nearby oppositely oriented gene.

Sylvie Gazzeri, PhD

Affiliation: INSERM U1209 (France)

Title: Altered splicing of ATG16-L1 contributes to acquired resistance of non-small cell lung cancer to EGFR-TKI through autophagy inhibition.

Guosheng Qu, PhD

Affiliation: Hebei University (China)

Title: Avaliable soon.

William Kelly, PhD

Affiliation: Emory University (United States)

Title: Avaliable soon.

Valer Gotea, PhD

Affiliation: National Human Genome Research Institute (United States)

Title: Avaliable soon.

Denis Dupuy, PhD

Affiliation: Inserm-Université de Bordeaux (France)

Title: Avaliable soon.

Marco Baralle, PhD

Affiliation: ICGEB (Italy)

Title: Avaliable soon.

Yuichi Shiraishi, PhD

Affiliation: National Cancer Center (Japan)

Title: Avaliable soon.

Petra Kleiblova, PhD

Affiliation: Charles University, First Faculty of Medicine, Institute of Biology and Medical Genetics (Czech Republic)

Title: NGS-based analyses of RNA as a tool in oncogenetics.

Martin Schroeder, PhD

Affiliation: Durham University (United Kingdom)

Title: An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response.

Nicola Jeffery, PhD

Affiliation: University of Exeter (United Kingdom)

Title: Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns.

Benjamin Lee, PhD

Affiliation: University of Exeter (United Kingdom)

Title: Negligible senescence in naked mole rats may be a consequence of well-maintained splicing regulation.

Jesús Valdés Flores, PhD

Affiliation: Departamento de Bioquímica, Centro de Investigación y de Estudios Avanzados (Mexico)

Title: Avaliable soon.

Maayan Salton, PhD

Affiliation: Hebrew University (Israel)

Title: KDM3A regulates alternative splicing of cell-cycle genes following DNA damage.

Logan Walker, PhD

Affiliation: University of Otago (New Zealand)

Title: Assessment of cancer susceptibility gene mRNA splicing with implications for variant classification.

Mihwa Lee, PhD

Affiliation: La Trobe University (Australia)

Title: Cytoplasmic accumulation of the RNA-binding protein SFPQ by zinc-induced polymerization.

Alexandra Filatova, PhD

Affiliation: Research Centre of Medical Genetics, Moscow (Russia)

Title: PAX6 5’-UTR mutations affecting splicing lead to a disruption of protein translation and cause Congenital aniridia.

Mikhail Skoblov, PhD

Affiliation: Laboratory of Functional Genomics, Research Centre for Medical Genetics (Russia)

Title: Approaches to the analysis of variants affecting splicing in hereditary diseases.

Shalini Sharma, PhD

Affiliation: University of Arizona, College of Medicine-Phoenix (United States)

Title: Impact of Splicing Factor Mutations on Human Hematopoietic Stem and Progenitor Cells.

Steven Fisher, PhD

Affiliation: University of Maryland School of Medicine (United States)

Title: Alternative splicing determines vascular smooth muscle function: Focus on myosin phosphatase splice variants and their targeting for therapeutic gain.

Erzsébet Fekete, PhD

Affiliation: University of Debrecen (Hungary)

Title: Avaliable soon.

Jiaqian Wu, PhD

Affiliation: The University of Texas Health Science Center at Houston (United States)

Title: An RNA-Sequencing Transcriptome and Splicing Database of Purified Cell Types of the Cerebral Cortex and Spinal Cord Injury.

Eiichi Saitoh, PhD

Affiliation: Graduate School of Technology, Niigata Institute of Technology (Japan)

Title: Expression of proline-rich proteins, P-B1, P-B, and BPLP, the parent proteins of opiorphin family, in human saliva.

Tracy Kress, PhD

Affiliation: The College of New Jersey (United States)

Title: Acetylation of Histones H4 and H2A.Z by the NuA4 acetyltransferase is Required for Appropriate RNA Splicing in Saccharomyces cerevisiae.

Beverly Chilton, PhD

Affiliation: Texas Tech University HSC (United States)

Title: Alternative splicing of helicase-like transcription factor (Hltf) promotes immune tolerance in murine placenta.

Xuhua Xia, PhD

Affiliation: University of Ottawa (Canada)

Title: Dissecting factors affecting splicing efficiency in yeast.

Anthony Purcell, PhD

Affiliation: Monash University (Australia)

Title: Peptide and protein splicing – fuelling the fires of autoimmunity.

Towfique Raj, PhD

Affiliation: Icahn School of Medicine at Mount Sinai (United States)

Title: Avaliable soon.

Benoit Coulombe, PhD

Affiliation: Montreal Clinical Research Institute (Canada)

Title: Avaliable soon.

John Kappler, PhD

Affiliation: National Jewish Health/Barbara Davis Center for Diabetes (United States)

Title: Formation of CD4 T cell Epitopes by Transpeptidation.

Giulia Fontemaggi, PhD

Affiliation: Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute (Italy)

Title: The ID4/mutant p53 protein complex enhances proliferation of breast cancer cells through the modulation of alternative splicing.

Kazuyuki Matsushita, PhD

Affiliation: Department of Laboratory Medicine & Division of Clinical Genetics and Proteomics, Chiba University Hospital (Japan)

Title: Posttranscriptional regulation of BRG1 by FIRΔexon2, a splicing variant from of PUF60, in cancers.

Ksenia S. Anufrieva, PhD

Affiliation: Moscow Institute of Physics and Technology (State University) (Russia)

Title: The combined effects of splicing inhibitors and DNA damaging drugs on cancer cell survival.

Nathalie Vigneron, PhD

Affiliation: Ludwig Institute for Cancer Research, Brussels (Belgium)

Title: Antigenic peptides produced by peptide splicing in the proteasome.

Wayne Paes, PhD

Affiliation: Nuffield Department of Clinical Medicine, University of Oxford (UK)

Title: Elucidating the signatures of proteasome-catalysed peptide splicing.

Juliane Liepe, PhD

Affiliation: Max-Planck-Institute for Biophysical Chemistry (Germany)

Title: SPI-ART and the frequency of spliced peptides in HLA class I immunopeptidomes.

Pouya Faridi, PhD

Affiliation: Monash University (Australia)

Title: Spliced HLA bound peptides, a new class of antigens for cancer immunotherapy.

Dorota Kaminska, PhD

Affiliation: Institute of Public Health and Clinical Nutrition, University of Eastern Finland (Finland)

Title: Obesity and weight loss-related alternative splicing in adipose tissue.

Veronica Arora, PhD

Affiliation: Institute of Genetics and Genomics, Sir Ganga Ram Hospital, New Delhi (India)

Title: The first case of antenatal presentation in COG related Congenital Disorders of Glycosylation: a novel splice site mutation.

Nicolas Wein, PhD

Affiliation: The Ohio State University (USA)

Title: AAV.U7 induced exon skipping for two mutational hotspots of the DMD gene (~6%) results in efficient exon skipping, protein restoration and force improvement.

Kim Jung-Wook, PhD

Affiliation: Seoul National University (Korea)

Title: Alteration of AMELX splicing causes enamel defects.

Wei Guo, PhD

Affiliation: University of Wisconsin-Madison (USA)

Title: Phosphorylation of RBM20 on RS Domain Plays A Key Role in The Development of Heart Failure.

Charles E. Chalfant, PhD

Affiliation: University of South Florida (USA)

Title: AKT phosphorylates hnRNP L inducing differential sequence specificity, induction of caspase 9b, and enhanced lung tumorigenesis.

Michele Mishto, PhD

Affiliation: King’s College London (UK)

Title: 2004-2020: what we know about post-translational peptide splicing.

Patty T. Wai, PhD

Affiliation: The Institute of Cancer Research, London (UK)

Title: Targeting hotspot SF3B1 mutations in cancer.

Julia E. Weigand, PhD

Affiliation: Technische Universität Darmstadt (Germany)

Title: Muscleblind-like 2 controls the hypoxia response of cancer cells.

Manuel D. Gahete, PhD

Affiliation: University of Cordoba (Spain)

Title: Dysregulated spliceosomic landscape in hepatocellular carcinoma: association with aggressive characteristics.

Eduardo Eyras, PhD

Affiliation: Australian National University (Australia)

Title: Unshackling transcriptomes from genome references.

Liliana Florea, PhD

Affiliation: Johns Hopkins University (United States)

Title: High performance tools for analysis of large collections of RNA-seq data.

Andrew Mackay, PhD

Affiliation: University of L’Aquila (Italy)

Title: Discovery, characterization and potential roles of a novel extra-short form NF-YAx splice variant in human neuroblastoma.

David Elliott, PhD

Affiliation: Newcastle University (United Kingdom)

Title: Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancer.

Fenghua Lan, PhD

Affiliation: Dongfang Hospital, Xiamen University School of Medicine (China)

Title: Alternative splicing of human FMR1 gene: a model of single-gene transcriptome and proteome.

Wojciech Makalowski, PhD

Affiliation: University of Muenster (Germany)

Title: Life cycle adapted upstream open reading frames (uORFs) in Trypanosoma congolense: A post-transcriptional approach to accurate gene regulation.

Enrico Schleiff, PhD

Affiliation: Goethe University & FIAS (Germany)

Title: Splicing as central regulatory element of the plant heat stress response.

Dmitri Pervouchine, PhD

Affiliation: Skolkovo Institute of Science and Technology (Russia)

Title: Global cross-regulatory network couples the expression and alternative splicing of RNA-binding proteins by nonsense-mediated mRNA decay.


Affiliation: XXX

Title: Avaliable soon.